They say the shooter was a previous worker at a store on the domain who was sacked in April. He took his own particular life after the killings.
There is no proposal the executioner was an individual from a subversive or fear based oppressor association, police say.
The shooting came seven days before the main commemoration of the Pulse dance club shooting in the city.
Forty-nine individuals were murdered in that occurrence.
‘Working environment brutality’
Orange County Sheriff Jerry Demings said police had touched base at the scene of the shooting to discover four individuals’ dead. A fifth worker kicked the bucket while being taken to doctor’s facility.
The sheriff said the killings were most likely connected to a work environment debate. They happened at a business that makes shades for recreational vehicles.
The shooter, 54, has not been named by police. The majority of the dead were representatives at the firm.
The aggressor is accepted to have assaulted an individual from staff in 2014, albeit no charges were documented, Mr Demings said.
In an announcement, Florida Governor Rick Scott censured a “silly demonstration of viciousness”.
“Over the previous year, the Orlando people group has been tested more than ever,” he said.
In last June’s assault, the deadliest mass shooting in present day US history, shooter Omar Mateen killed 49 individuals and harmed handfuls more at a gay club before being shot dead by police.